Therapy For Lupus:
Scientists from Northwestern Medicine have brought new hope to patients with lupus. A new non toxic therapy For Lupus that suppresses lupus in blood samples was designed and successfully tested on patients with the autoimmune disease.There is hope this treatment will replace the use of toxic drugs that carry nasty side effects with a vaccine like therapy For Lupus. This new treatment could keep lupus in remission in the body.Lupus is a debilitating autoimmune disease where the body creates auto-antibodies that attack its own healthy tissue. This causes severe pain, inflammation and destruction to many vital organs in the body. The Lupus Foundation of America has estimated that some form of the disease affects 5 million people throughout the world.Previous studies at Northwestern have showed that a non toxic therapy for lupus using small pieces of proteins known as peptides can block lupus in mice prone to contracting the disease. The peptides produce special regulatory T cells that are vital to suppressing the disease.
This new study was comprised of 30 lupus patients, ten of whom were active and twenty who were in remission, along with fifteen healthy patients. Each person had a blood sample cultured with low doses of the peptide.Senior study author Syamal Datta, professor of medicine-rheumatology and microbiology-immunology at Northwestern University Feinberg School of Medicine, said, “We found that the peptides could not only generate regulatory T cells, but also that they block and reduce autoantibody production to almost baseline levels in the blood cultures from people with active therapy for Lupus.”